Clinical Trials

Phase 2 Active not recruiting

Thymic epithelial tumor, Thymoma, Thymus Neoplasms

NCT03463460 2026-03-23

Pembrolizumab and Sunitinib Malate in Treating Participants With Refractory Metastatic or Unresectable Thymic Cancer

9 enrolled

Phase 2 Not yet recruiting

Thymoma

NCT07479628 2026-03-18

Neoadjuvant Adebrelimab Plus CRT for Locally Advanced Thymic Carcinoma

31 enrolled

Thymoma

NCT07132918 2026-03-11

HEARTS Trial for Thoracic Cancers

Phase 2/3 Not yet recruiting

60 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Thymoma

NCT07463313 2026-03-11

6 vs 3 Cycles of Neoadjuvant Chemotherapy for Potentially Resectable Locally Advanced Thymic Epithelial Tumors

116 enrolled

Phase NA Active not recruiting

Thymic epithelial tumor, Mediastinal Neoplasms, Thymoma

NCT03968315 2026-03-09

An Investigational Scan (MRI) in Imaging Patients With Newly-Diagnosed or Recurrent Thymoma

40 enrolled

Thymoma

NCT04710628 2026-02-19

PECATI

43 enrolled

GastrointestinalGynecologicOther solid neoplasmThoracic

Thymoma

NCT06885697 2026-02-17

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

Phase 1 Recruiting

100 enrolled

Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thymoma, Thymus Neoplasms

NCT07328074 2026-02-05

Electrocautery Resection Combined With HITHOC for Thymic Epithelial Tumors With Pleural Metastasis

Not yet recruiting

70 enrolled

Thymic epithelial tumor, Thymoma

NCT03295227 2026-01-30

Pembrolizumab in Treating Participants With Unresectable Thymoma or Thymic Cancer

Phase 1 Recruiting

37 enrolled

Thymoma

NCT06248515 2026-01-27

A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial Tumors

18 enrolled

Phase 2 Active not recruiting

Thymoma

NCT01025089 2026-01-07

Chemotherapy Plus Cetuximab Followed by Surgical Resection in Patients With Locally Advanced or Recurrent Thymoma or Thymic Carcinoma

18 enrolled

Phase 1 Active not recruiting

Thymoma

NCT05544929 2026-01-06

A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers

126 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Nasopharyngeal Carcinoma, Anus Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Intestinal Neoplasms, Kidney Neoplasms, Lung Neoplasms, Melanoma, Mesothelioma, Nasopharyngeal Neoplasms, Neoplasms, Ovarian Neoplasms, Rectal Neoplasms, Skin Neoplasms, Thymoma, Thymus Neoplasms, Colorectal Neoplasms, Adenocarcinoma, Clear Cell, Triple Negative Breast Neoplasms

NCT01385722 2025-12-26

Molecular Analysis of Thoracic Malignancies

Enrolling by invitation

1,000 enrolled

Other solid neoplasmThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Mesothelioma, Thymoma, Thymus Neoplasms

NCT05150210 2025-12-23

SP Thoracic IDE Study

Phase NA Active not recruiting

32 enrolled 8 charts

Myasthenia Gravis, Thymoma

NCT06838910 2025-12-01

Tislelizumab Combined With Anlotinib as Second-line Therapy in Thymoma and Thymic Carcinoma

20 enrolled

Thymoma

NCT03694002 2025-10-30

Carboplatin and Paclitaxel With or Without Ramucirumab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Thymic Cancer That Cannot Be Removed by Surgery

21 enrolled 17 charts

Thymoma

NCT06790706 2025-10-06

IMMUNORARE5

EndocrineGastrointestinalGynecologicHead & NeckNETThoracic

154 enrolled

Gastro-enteropancreatic neuroendocrine tumor, Carcinoid Tumor, Thymoma, Gestational Trophoblastic Disease, Thyroid Carcinoma, Anaplastic

NCT07181720 2025-10-02

CD70-Targeted CAR-T Therapy in CD70-Positive Advanced Solid Tumors

Phase 1 Recruiting

90 enrolled

EndocrineGenitourinaryGynecologicHead & NeckThoracic

Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Thymoma, Thyroid Carcinoma, Anaplastic

NCT07179341 2025-09-17

Survival Nomogram for Patients With Thymic Carcinoma

Phase NA Completed

156 enrolled

Thymoma

NCT06186726 2025-06-13

Clinical Study of Carbon Ion Radiotherapy Combined With Chemotherapy for Thymic Epithelial Tumors

48 enrolled

Thymoma

NCT05667948 2025-05-22

Molecular Analysis and Treatment Options of Thymic Malignancies

Recruiting

500 enrolled

Thymic epithelial tumor, Thymoma, Thymus Neoplasms

NCT06545409 2025-03-25

SPRATS

Phase NA Recruiting

28 enrolled

Thymoma

NCT05255965 2025-01-16

IL-8+ naïve T Cells as a Biomarker for Thymoma Identification

Completed

310 enrolled

Thymoma

NCT06730308 2024-12-12

Glucocorticoids Combined With Concurrent Chemoradiotherapy for Unresectable Thymoma

45 enrolled

BreastEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Thymoma

NCT04985357 2024-11-25

Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs

Withdrawn

Anus Neoplasms, Appendiceal Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Laryngeal Neoplasms, Lip Neoplasms, Lung Neoplasms, Mesothelioma, Mouth Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Paranasal Sinus Neoplasms, Penile Neoplasms, Prostatic Neoplasms, Thymoma, Vulvar Neoplasms, Pleural Effusion, Malignant, Carcinoma, Neuroendocrine, Cholangiocarcinoma, Carcinoma, Ductal, Small Cell Lung Carcinoma

NCT06692062 2024-11-18

Hypofractionated Radiotherapy for Thymic Epithelial Tumors

Phase NA Recruiting

100 enrolled

Thymic epithelial tumor, Thymoma, Thymus Neoplasms

NCT03583086 2024-10-08

Phase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic Tumors

Phase 1/2 Completed

88 enrolled 20 charts

Carcinoma, Non-Small-Cell Lung, Thymoma, Small Cell Lung Carcinoma

NCT01306045 2024-10-01

Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies

647 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Thymoma, Small Cell Lung Carcinoma

NCT01621568 2024-09-24

Sunitinib for Advanced Thymus Cancer Following Earlier Treatment

56 enrolled 15 charts

Thymoma, Thymus Neoplasms

NCT05214612 2024-07-31

Predictors and Prognostic Factors of Myasthenia Gravis Outcome

Recruiting

30 enrolled

BreastGastrointestinalLymphoidSarcomaThoracic

Myasthenia Gravis, Nervous System Diseases, Thymoma, Thymus Hyperplasia, Autoimmune Diseases of the Nervous System, Neuromuscular Junction Diseases

NCT04072393 2024-07-12

Cardiac Rehabilitation for Patients Receiving Radiation Therapy for Thoracic Cancers

Phase NA Terminated

24 enrolled

Breast Neoplasms, Esophageal Neoplasms, Hodgkin Disease, Lung Neoplasms, Lymphoma, Non-Hodgkin, Sarcoma, Thymoma

NCT04321330 2024-06-11

A Study to Investigate the Efficacy and Safety of Atezolizumab (Tecentriq) in Previously-Treated Patients With Advanced Thymic Carcinoma

34 enrolled