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Phase

Phase 1/2 2

Status

Withdrawn 1Completed 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Tumor-Agnostic 1Myeloid 1Classical hematology 1

Conditions

Neoplasms 1Myeloproliferative Disorders 1Anemia, Refractory, with Excess of Blasts 1

Interventions

Cisplatin 3205Cyclophosphamide 3200Carboplatin 2979Radiotherapy 2790Paclitaxel 2720Gemcitabine 2573pembrolizumab 2388Bevacizumab 2210Docetaxel 2200Fluorouracil 1851Capecitabine 1834Oxaliplatin 1742Dexamethasone 1606Nivolumab 1581Doxorubicin 1503Rituximab 1489Magnetic Resonance Spectroscopy 1391Etoposide 1346Irinotecan 1248Leucovorin 1227Drug Therapy 1205Cytarabine 1131Pemetrexed 1078fludarabine 1065Specimen Handling 1021Vincristine 966Trastuzumab 946Cetuximab 945Prednisone 943Lenalidomide 938

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
ASTX029 × Clear all
NCT06284460 2026-02-13

Phase I/II Study of a Combination of Decitabine and Cedazuridine (ASTX727) and ASTX029, an ERK Inhibitor, for Patients With RAS Pathway Mutant Myelodysplastic Syndromes and Myelodysplastic/Myeloproliferative Neoplasms

M.D. Anderson Cancer Center

Phase 1/2 Withdrawn
Classical hematologyMyeloid

Anemia, Refractory, with Excess of Blasts, Myeloproliferative Disorders

NCT03520075 2025-07-03

Study of ASTX029 in Subjects With Advanced Solid Tumors

Taiho Oncology, Inc.

Phase 1/2 Completed
192 enrolled 56 charts
Tumor-Agnostic

Neoplasms

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