Clinical Trials Browser

Dactinomycin × Clear all

NCT02567435 2026-05-27

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Phase 3 Active not recruiting

325 enrolled 14 charts

Rhabdomyosarcoma, Rhabdomyosarcoma, Alveolar, Rhabdomyosarcoma, Embryonal

NCT07194044 2026-05-15

METTSEO

Phase 1 Recruiting

Sarcoma, Ewing

NCT04994132 2026-05-05

A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk Rhabdomyosarcoma

Phase 3 Active not recruiting

Rhabdomyosarcoma, Rhabdomyosarcoma, Alveolar, Rhabdomyosarcoma, Embryonal

NCT05304585 2026-05-05

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

Phase 3 Recruiting

Rhabdomyosarcoma, Embryonal

NCT06401330 2026-05-05

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Phase 3 Recruiting

Stage I Mixed Cell Type Kidney Wilms Tumor

NCT06647953 2026-05-05

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

Phase 3 Recruiting

Pleuropulmonary blastoma

NCT01871766 2026-04-24

Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

Phase 2 Active not recruiting

Rhabdomyosarcoma

NCT04332874 2026-04-23

A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

Phase 2 Recruiting

Sarcoma, Dermatofibrosarcoma, Sarcoma, Alveolar Soft Part, Histiocytoma, Malignant Fibrous

NCT00379340 2026-03-17

Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed Stage III or Stage IV Wilms' Tumor

Phase 3 Active not recruiting

395 enrolled 15 charts

Wilms Tumor

NCT07466316 2026-03-12

A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

Phase 3 Not yet recruiting

Rhabdomyosarcoma

NCT00352534 2026-02-18

Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' Tumor

Phase 3 Active not recruiting

808 enrolled 11 charts

Wilms Tumor

NCT04388839 2025-11-26

Evolutionary Therapy for Rhabdomyosarcoma

Phase 2 Active not recruiting

Rhabdomyosarcoma, Sarcoma

NCT06023641 2025-08-19

Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease

Phase 2 Recruiting

Rhabdomyosarcoma

NCT04562558 2025-08-11

Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia

Phase NA Active not recruiting

Hydatidiform Mole, Invasive, Choriocarcinoma, Gestational Trophoblastic Disease

NCT00945009 2025-05-31

Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor

Phase 3 Active not recruiting

249 enrolled 14 charts

Beckwith-Wiedemann Syndrome, Wilms Tumor

NCT06028672 2025-02-06

TA56

Phase NA Recruiting

Gestational Trophoblastic Disease

NCT06020755 2024-12-31

TA7

Phase 2 Recruiting

Gestational Trophoblastic Disease

NCT04625907 2024-05-23

FaR-RMS

Phase 1/2 Recruiting

Rhabdomyosarcoma

NCT06309732 2024-03-13

GAMEC-II

Phase 2 Completed

Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT00354835 2023-01-31

Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma

Phase 3 Completed

481 enrolled 21 charts

Rhabdomyosarcoma, Sarcoma

NCT02063022 2022-09-19

EW-1

Phase 3 Completed

Sarcoma, Ewing

NCT01535053 2022-08-12

Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia

Phase 3 Completed

57 enrolled 12 charts

Choriocarcinoma, Hydatidiform Mole

NCT02639650 2022-06-03

Study of Paclitaxel Plus Cisplatin as the First-line Chemotherapy in High Risk Gestational Trophoblastic Tumor

Phase 3 Unknown

Gestational Trophoblastic Disease

NCT00075582 2021-11-19

Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk Rhabdomyosarcoma

Phase 3 Completed

390 enrolled 14 charts

Rhabdomyosarcoma

NCT00002611 2021-02-25

Combination Chemotherapy Alone or With Radiation Therapy in Treating Children With Kidney Cancer

Phase 3 Completed

Kidney Neoplasms, Wilms Tumor

NCT00354744 2020-01-29

High-Dose Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Metastatic Rhabdomyosarcoma or Ectomesenchymoma

Phase 3 Completed

109 enrolled 12 charts

Malignant mesenchymal tumor, Rhabdomyosarcoma, Sarcoma

NCT01823315 2019-12-24

GTN-01

Phase 3 Unknown

Gestational Trophoblastic Disease

NCT01014767 2019-08-20

Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors

Phase 3 Terminated

27 enrolled 1 chart

Brain Neoplasms, Choroid Plexus Neoplasms

NCT00003702 2018-05-15

Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia

Phase 3 Completed

240 enrolled 9 charts

Hydatidiform Mole

NCT01323517 2018-05-15

Addition of Ipilimumab (MDX-010) To Isolated Limb Infusion (ILI) With Standard Melphalan and Dactinomycin In The Treatment of Advanced Unresectable Melanoma of The Extremity

Phase 2 Completed

26 enrolled 11 charts

Melanoma

NCT01055314 2017-08-29

Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma

Phase 2 Completed

175 enrolled 13 charts

Rhabdomyosarcoma, Sarcoma

NCT00335556 2017-07-21

Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors

Phase 2 Completed

291 enrolled 18 charts

Carcinoma, Renal Cell, Wilms Tumor

NCT00002766 2016-02-22

Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma

Phase 3 Completed

170 enrolled 7 charts

LymphoidMyeloidOther hematologic neoplasm

Blast Crisis, Leukemia, Lymphoma, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00084838 2015-12-24

Chemotherapy Combined With Radiation Therapy for Newly Diagnosed CNS AT/RT

Phase 2 Completed

25 enrolled 24 charts

Central Nervous System Neoplasms, Rhabdoid Tumor

NCT00072280 2014-09-30

Surgery and/or Chemotherapy in Treating Children With Infantile, Congenital, or Childhood Fibrosarcoma

Phase 2 Terminated

7 enrolled 9 charts

Fibrosarcoma, Sarcoma

NCT00002610 2014-07-25

Chemotherapy With or Without Surgery, Radiation Therapy, or Stem Cell Transplantation in Treating Young Patients With Kidney Tumors

Phase 3 Completed

Kidney Neoplasms, Wilms Tumor

NCT01531244 2014-07-18

Isolated Limb Infusion Chemotherapy With Targeted Gene Therapy for Advanced, Unresectable Extremity Melanoma

Phase 1/2 Withdrawn

Melanoma

NCT00003804 2014-06-24

Chemotherapy Plus Surgery in Treating Children at Risk of or With Stage I Wilms' Tumor

Phase 3 Unknown

Kidney Neoplasms, Wilms Tumor

NCT00020566 2014-06-24

Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients With Ewing's Sarcoma

Phase 3 Unknown

Sarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00047138 2014-06-24

Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor

Phase 3 Unknown

Kidney Neoplasms, Wilms Tumor

NCT00002995 2014-02-14

Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma

Phase 3 Completed

Malignant mesenchymal tumor, Rhabdomyosarcoma, Sarcoma

NCT00003955 2014-02-14

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Metastatic Rhabdomyosarcoma or Sarcoma

Phase 2 Completed

Malignant mesenchymal tumor, Rhabdomyosarcoma, Sarcoma

NCT00002898 2013-12-04

Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma

Phase 3 Completed

Malignant mesenchymal tumor, Hemangiopericytoma, Malignant, Fibrosarcoma, Hemangiosarcoma, Liposarcoma, Sarcoma, Neuroectodermal Tumors, Primitive, Peripheral, Desmoplastic Small Round Cell Tumor

NCT00025441 2013-12-04

Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors

Phase 2 Completed

GynecologicSarcoma

Malignant mesenchymal tumor, Hemangiopericytoma, Malignant, Chondrosarcoma, Fibrosarcoma, Hemangiosarcoma, Liposarcoma, Ovarian Neoplasms, Sarcoma, Neuroectodermal Tumors, Primitive, Peripheral, Desmoplastic Small Round Cell Tumor

NCT00002516 2013-09-17

Combination Chemotherapy Plus Surgery and Radiation Therapy in Treating Patients With Ewing's Sarcoma

Phase 3 Unknown

Sarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00245089 2013-08-12

Vincristine, Dactinomycin, and Cyclophosphamide in Treating Patients With Embryonal Rhabdomyosarcoma

Phase 2 Unknown

Sarcoma

NCT00245141 2013-08-12

Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Embryonal Rhabdomyosarcoma

Phase 2 Unknown

Sarcoma

NCT00379457 2013-08-12

Combination Chemotherapy in Treating Young Patients With Nonmetastatic Rhabdomyosarcoma

Phase 3 Unknown

Malignant mesenchymal tumor, Sarcoma

NCT00025103 2013-08-02

Chemotherapy Followed by Surgery and Radiation Therapy With or Without Stem Cell Transplant in Treating Patients With Relapsed or Refractory Wilms' Tumor or Clear Cell Sarcoma of the Kidney

Phase 2 Unknown

Kidney Neoplasms, Wilms Tumor

NCT00002489 2013-06-26

Combination Chemotherapy in Treating Children With Non-testicular Malignant Germ Cell Tumors

Phase 2 Completed

Teratoma, Ovarian, Ovarian Neoplasms