Clinical Trials Browser

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NCT03678350 2026-03-27

Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery

Phase 1 Completed

Other solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Pleural Diseases

NCT04836429 2026-02-04

Photodynamic Therapy to Amplify the Response to Immunotherapy in Patients With Non-small Cell Lung Cancer With Pleural Disease

Phase 1 Terminated

Carcinoma, Non-Small-Cell Lung, Pleural Diseases

NCT02153229 2025-12-26

MPM-PDT

Phase 2 Active not recruiting

Other solid neoplasmThoracic

Epitheliod Malignant Pleural Mesothelioma

NCT03735095 2025-04-16

Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer

Phase 1/2 Terminated

19 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT03727061 2025-03-11

Porfimer Sodium Interstitial Photodynamic Therapy With or Without Standard of Care Chemotherapy in Treating Patients With Locally Advanced or Recurrent Head and Neck Cancer

Phase 1 Terminated

5 enrolled 8 charts

Recurrent Head and Neck Carcinoma

NCT04753918 2021-02-15

Novel Light Delivery Methods for Lung Cancer Photodynamic Therapy - A Pilot Study

Phase EARLY_PHASE1 Unknown

Carcinoma, Non-Small-Cell Lung

NCT00601848 2020-11-24

Photodynamic Therapy in Treating Patients With Resectable Non-Small Cell Lung Cancer That Has Spread to the Pleura

Phase 2 Terminated

9 enrolled 5 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Pleural Effusion, Malignant

NCT02916745 2020-03-04

Feasibility Study of Using Navigational Bronchoscopy to Perform PDT-Photofrin® in Unresectable Peripheral Lung Cancer

Phase 1 Completed

5 enrolled 30 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03344861 2020-01-13

Safety of PDT-Photofrin® Prior to Lung Surgery

Phase 1 Completed

10 enrolled 27 charts

Lung Neoplasms

NCT02106559 2019-03-21

Photodynamic Therapy During Surgery in Treating Patients With Pleural Malignancy

Phase NA Withdrawn

Other solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT01682746 2019-02-25

Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors

Phase 1 Completed

CNSEndocrineSarcoma

Astrocytoma, Brain Neoplasms, Chordoma, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pituitary Neoplasms, Germinoma, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Optic Nerve Glioma

NCT01770132 2018-12-13

Ultrasound-Guided Photodynamic Therapy With Photofrin & Gemcitabine for Patients With Locally Advanced Pancreatic Cancer

Phase 1 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT00754910 2018-07-05

Photodynamic Therapy Using Porfimer Sodium in Treating Patients With Non-Small Cell Lung Cancer And Bronchial Disease

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02068157 2017-10-11

Interstitial Photodynamic Therapy in Treating Patients With Recurrent Head and Neck Cancer

Phase 2 Terminated

3 enrolled 8 charts

Lymphoid Interstitial Pneumonia, Squamous Cell Carcinoma of Head and Neck, Tongue Neoplasms

NCT00453336 2017-02-08

Photodynamic Therapy With Porfimer Sodium in Treating Patients With Precancerous Lesions, Cancer, or Other Disease of the Aerodigestive Tract

Phase 2 Completed

45 enrolled 9 charts

Head & NeckOther neoplasm

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Leukoplakia, Oral, Precancerous Conditions

NCT00217087 2015-12-24

Endoscopic Therapy of Early Cancer in Barretts Esophagus

Phase 2 Completed

73 enrolled 9 charts

Gastrointestinal

Barrett Esophagus

NCT02628665 2015-12-11

Clinical Study of Time Optimizing of Endoscopic Photodynamic Therapy on Esophageal and/or Gastric Cardiac Cancer

Phase 3 Unknown

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma

NCT01506115 2015-11-20

Safety and Efficacy of Photodynamic Therapy for Bile Duct Invasion of Hepatocellular Carcinoma

Phase NA Completed

Gastrointestinal

Carcinoma, Hepatocellular, Jaundice, Obstructive

NCT00530088 2014-07-04

Photodynamic Therapy Using Porfimer Sodium in Treating Patients With Recurrent Mouth or Throat Dysplasia or Recurrent In Situ Cancer or Stage I Cancer of the Mouth or Throat

Phase NA Terminated

30 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms

NCT00003788 2013-11-06

Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas

Phase 3 Unknown

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00253617 2013-04-04

Stent Placement With or Without Photodynamic Therapy Using Porfimer Sodium as Palliative Treatment in Treating Patients With Stage III or Stage IV Cholangiocarcinoma That Cannot Be Removed By Surgery

Phase 3 Withdrawn

Gastrointestinal

Bile Duct Neoplasms, Gallbladder Neoplasms

NCT00003923 2013-03-04

Photodynamic Therapy in Treating Patients With Cancer of the Bile Duct, Gallbladder, or Pancreas

Phase 2 Completed

Gastrointestinal

Bile Duct Neoplasms, Gallbladder Neoplasms, Liver Neoplasms, Pancreatic Neoplasms

NCT00513539 2013-02-20

Photostent-02

Phase 3 Completed

Gastrointestinal

Bile Duct Neoplasms, Gallbladder Neoplasms

NCT00002964 2013-02-05

Porfimer Sodium in Diagnosing Patients With Head and Neck Cancer

Phase 2 Completed

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT00322699 2012-10-26

Sequential Whole Bladder Photodynamic Therapy (WBPDT) in the Management of Superficial Bladder Cancer

Phase 1/2 Completed

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms, Photosensitivity Disorders

NCT00002935 2011-12-23

Photodynamic Therapy in Treating Patients With Early Esophageal Cancer

Phase 2 Completed

Gastrointestinal

Esophageal Neoplasms

NCT00054002 2011-03-01

Surgery and Photodynamic Therapy in Treating Patients With Malignant Mesothelioma

Phase 2 Completed

Other solid neoplasmThoracic

Mesothelioma, Malignant, Solitary Fibrous Tumor, Pleural

NCT00118222 2010-06-11

High Light and Low Light Dose PDT in Glioma

Phase 3 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma