Clinical Trials

Polycythemia Vera

NCT04116502 2026-04-28

MITHRIDATE

Phase 3 Recruiting

586 enrolled

Polycythemia Vera

NCT07190833 2026-04-09

A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor Patients (South Korea)

Phase 1 Not yet recruiting

27 enrolled

Other solid neoplasm

Treatment-Refractory Solid Tumors

NCT07170592 2026-04-07

A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor Patients

24 enrolled

Other solid neoplasm

Treatment-Refractory Solid Tumors

NCT06093672 2026-03-25

GIV-IN-PV

Phase 3 Recruiting

220 enrolled

Polycythemia Vera

NCT06871410 2026-03-24

Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

26 enrolled

Phase 2 Not yet recruiting

Leukemia, Myeloid, Acute

NCT06930352 2026-03-13

Ziftomenib for the Treatment of Patients With NPM1 Mutated or KMT2A Rearranged Acute Myeloid Leukemia Not Eligible for Standard Therapy

70 enrolled

Leukemia, Myeloid, Acute

NCT06063317 2026-03-06

OASIS

Phase 1 Terminated

25 enrolled

Bites and Stings

NCT07033598 2026-03-05

PROSPERA

Phase 2 Recruiting

66 enrolled

Leukemia, Myelomonocytic, Chronic

NCT05526924 2026-03-04

Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With Previously Treated Head and Neck Cancer

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04217356 2026-01-26

ALLO-BAT

Active not recruiting

90 enrolled

Phase 2 Active not recruiting

Bone Marrow Neoplasms, Primary Myelofibrosis

NCT05020652 2025-12-17

A Clinical Trial of TQ05105 Tablets in the Treatment of Moderate and High Risk Myelofibrosis

107 enrolled

Lymphoid

Lymphoma, Follicular

NCT06326190 2025-09-16

LUMEN-1

Phase 2 Recruiting

136 enrolled

LymphoidOther hematologic neoplasm

Meningioma

NCT03860844 2025-09-09

ISAKIDS

Phase 2 Terminated

67 enrolled 25 charts

Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05548062 2025-09-03

Prospero

Active not recruiting

242 enrolled

Polycythemia Vera

NCT06199557 2025-06-29

HUVAMER

Phase 1/2 Recruiting

48 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT06005324 2025-06-08

Personalized, Adaptive Treatment for Locally Advanced Head and Neck Cancer

36 enrolled

HPV-Negative Squamous Cell Carcinoma

NCT03944915 2025-05-11

DEPEND

35 enrolled 14 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT03107182 2025-05-06

OPTIMA-II

72 enrolled 14 charts

Squamous Cell Carcinoma of Head and Neck

NCT04126681 2025-03-03

A Pivotal Study of HQP1351 in Patients With Chronic Myeloid Leukemia in Chronic Phase

144 enrolled

Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT02258659 2024-09-24

OPTIMA

62 enrolled 13 charts

Squamous Cell Carcinoma of Head and Neck, Papillomavirus Infections

NCT05005182 2024-09-19

Luspatercept With or Without Hydroxyurea for the Treatment of Myelodysplastic/Myeloproliferative Neoplasms With Ring Sideroblasts and Thrombocytosis or Unclassifiable With Ring Sideroblasts

Phase 2 Terminated

3 enrolled 12 charts

Myeloproliferative Disorders, Thrombocytosis

NCT01847326 2024-07-31

Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer

Phase 1 Completed

48 enrolled

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT02626715 2024-07-16

Reduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS

21 enrolled 24 charts

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT01693718 2024-01-29

A Multicenter Study of Intensive Concomitant Chemoradiotherapy With Filgrastim (GCSF) for Patients With Locoregionally Advanced Head and Neck Cancer

44 enrolled

Laryngeal Diseases, Neoplasms

NCT00002868 2023-06-22

Interferon-alfa With or Without Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia

744 enrolled

Leukemia, Leukemia, Myeloid, Chronic-Phase

NCT01711541 2023-06-07

Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IV Head and Neck Cancer

Phase 1/2 Completed

24 enrolled 12 charts

Squamous Cell Carcinoma of Head and Neck, Oropharyngeal Neoplasms

NCT02088541 2023-01-26

SOPRA

317 enrolled 25 charts

Leukemia, Myeloid, Acute

NCT01387763 2022-04-27

DALIAH

202 enrolled

Polycythemia Vera, Thrombocythemia, Essential, Primary Myelofibrosis

NCT02899169 2021-09-08

APL16

Phase 3 Unknown

110 enrolled

Leukemia, Promyelocytic, Acute

NCT00006119 2021-02-21

Hydroxyurea in Treating Patients With Recurrent and/or Unresectable Meningioma

Brain Neoplasms, Meningioma, Central Nervous System Neoplasms

NCT03463733 2020-10-08

HUTMZ

Phase 1 Unknown

54 enrolled

Glioblastoma, Glioma

NCT00928707 2019-10-31

PV

45 enrolled 10 charts

Polycythemia Vera

NCT00468169 2019-10-09

EPIC

110 enrolled 14 charts

Carcinoma, Head and Neck Neoplasms, Neoplasms

NCT01964755 2019-09-23

Chemotherapy for Relapsed Epstein Barr Virus Associated Lymphoma

Phase 2 Terminated

6 enrolled 14 charts

Lymphoid

Hodgkin Disease, Lymphoma, Non-Hodgkin, Epstein-Barr Virus Infections

NCT01259856 2019-04-30

Randomized Trial of Pegylated Interferon Alfa-2a Versus Hydroxyurea in Polycythemia Vera (PV) and Essential Thrombocythemia (ET)

168 enrolled 16 charts

Polycythemia Vera, Thrombocythemia, Essential

NCT01243944 2019-03-06

Study of Efficacy and Safety in Polycythemia Vera Subjects Who Are Resistant to or Intolerant of Hydroxyurea: JAK Inhibitor INC424 (INCB018424) Tablets Versus Best Available Care: (The RESPONSE Trial)

222 enrolled 21 charts

Polycythemia Vera

NCT00019474 2018-09-14

Combination Chemotherapy Plus Interferon Alfa Followed by Filgrastim in Treating Patients With Gastrointestinal Tract Cancer

60 enrolled

Gastrointestinal

Bile Duct Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT03515018 2018-05-22

HU

Phase 3 Unknown

60 enrolled

Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT00055874 2018-05-03

Imatinib Mesylate With or Without Interferon Alfa or Cytarabine Compared With Interferon Alfa Followed by Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia

1,551 enrolled

Leukemia, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT00117572 2018-04-09

DeCIDE

285 enrolled 22 charts

Laryngeal Neoplasms, Paranasal Sinus Neoplasms, Pharyngeal Neoplasms

NCT00462735 2018-03-13

Fluorouracil, Hydroxyurea, Cetuximab and Twice-daily Intensity Radiation Therapy for Advanced Head and Neck Cancer

33 enrolled 15 charts

Head and Neck Neoplasms, Laryngeal Neoplasms, Nose Neoplasms, Paranasal Sinus Neoplasms, Pharyngeal Neoplasms

NCT01632904 2017-11-14

Randomized Switch Study From Hydroxyurea to Ruxolitinib for RELIEF of Polycythemia Vera Symptoms: The Relief Study

110 enrolled 11 charts

Polycythemia Vera

NCT01211938 2017-05-16

JANORL2

Phase 2/3 Completed

60 enrolled

Carcinoma, Squamous Cell, Recurrence

NCT00978146 2017-04-20

Effect of Hydroxyurea as Treatment for Primary Desmoid Tumors

Phase 2 Withdrawn

Sarcoma

Fibroma, Desmoid Tumors

NCT00706810 2017-04-13

Combination of Hydroxyurea and Verapamil for Refractory Meningiomas

8 enrolled 5 charts

Brain Neoplasms, Meningioma, Neoplasms

NCT01949805 2016-11-28

PROUD-PV

257 enrolled

Polycythemia Vera

NCT00004933 2016-07-04

Homoharringtonine Compared With Hydroxyurea for Chronic Myelogenous Leukemia That Has Not Responded to Interferon Alfa

Phase 3 Terminated

5 enrolled

Leukemia, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT00003590 2016-05-20

S9811 Hydroxyurea in Treating Patients With Unresectable Benign Meningioma

29 enrolled 5 charts