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Phase

Phase 1 3Phase 2 1

Status

Completed 3Terminated 1

Sponsor Class

INDUSTRY 4

Study Type

Interventional 4

Sponsor

Cancer Type

Breast 2Gastrointestinal 1

Conditions

Breast Neoplasms 2Stomach Neoplasms 1Neoplasm Metastasis 1HER-2 Gene Amplification 1Esophageal Neoplasms 1

Interventions

Cisplatin 3205Cyclophosphamide 3200Carboplatin 2979Radiotherapy 2790Paclitaxel 2720Gemcitabine 2573pembrolizumab 2388Bevacizumab 2210Docetaxel 2200Fluorouracil 1851Capecitabine 1834Oxaliplatin 1742Dexamethasone 1606Nivolumab 1581Doxorubicin 1503Rituximab 1489Magnetic Resonance Spectroscopy 1391Etoposide 1346Irinotecan 1248Leucovorin 1227Drug Therapy 1205Cytarabine 1131Pemetrexed 1078fludarabine 1065Specimen Handling 1021Vincristine 966Trastuzumab 946Cetuximab 945Prednisone 943Lenalidomide 938

Date Range

30 days90 days1 yearAll

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Clinical Trials

4 trials
RecentStart dateEnrollment
MM-111 × Clear all
NCT01774851 2017-06-22

A Study of MM-111 and Paclitaxel With Trastuzumab in Patients HER2 Positive Carcinomas of the Distal Esophagus, Gastroesophageal (GE) Junction and Stomach

Merrimack Pharmaceuticals

Phase 2 Terminated
84 enrolled 10 charts
Gastrointestinal

Esophageal Neoplasms, Neoplasm Metastasis, Stomach Neoplasms

NCT01304784 2015-12-16

A Study of MM-111 in Combination With Multiple Treatments in Patients With HER2 Positive Cancer

Merrimack Pharmaceuticals

Phase 1 Completed
100 enrolled

HER-2 Gene Amplification

NCT00911898 2015-01-13

Monotherapy

Merrimack Pharmaceuticals

Phase 1 Completed
20 enrolled 5 charts
Breast

Breast Neoplasms

NCT01097460 2015-01-07

MM-111 in Combination With Herceptin in Patients With Advanced Her2 Amplified, Heregulin Positive Breast Cancer

Merrimack Pharmaceuticals

Phase 1 Completed
16 enrolled 7 charts
Breast

Breast Neoplasms

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