Clinical Trials Browser

Megestrol Acetate × Clear all

NCT04939090 2026-04-13

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

Phase 3 Active not recruiting

Other hematologic neoplasm

Anorexia, Hematologic Neoplasms

NCT05538897 2026-04-13

Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers

Phase 1/2 Active not recruiting

FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma

NCT06979596 2026-04-13

OMAHA-015

Phase 2 Recruiting

Neoplasms

NCT07462663 2026-04-09

SHAPE-ENDO

Not yet recruiting

GynecologicOther

Endometrial Hyperplasia, Neoplasms, Obesity, Endometrial Neoplasms, Overweight

NCT07319429 2026-03-13

FEMUS

Phase 2/3 Recruiting

Endometrial Neoplasms

NCT07436793 2026-02-27

Progestins for the Treatment of Endometrial Cancer or Precancers of the Uterus Before Surgery, The Pro-Window Trial

Phase 2 Not yet recruiting

Endometrial Hyperplasia

NCT06671548 2026-02-02

Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Recruiting

Leiomyoma, Menorrhagia

NCT04576104 2026-01-21

Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

Phase 2 Active not recruiting

Endometrial Hyperplasia, Endometrial Neoplasms

NCT03671811 2026-01-06

Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomy

Phase 2 Active not recruiting

44 enrolled 12 charts

Endometrial Hyperplasia, Endometrial Neoplasms

NCT06998758 2025-12-12

MATRIX

Phase 3 Recruiting

Weight Loss

NCT07254416 2025-11-28

A Study on Nausea and Vomiting Caused by T-DXd in Breast Cancer Patients

Phase 4 Not yet recruiting

Breast Cancer Patients Treated With T-DXd

NCT04491643 2025-08-11

Megestrol Acetate Plus Rosuvastatin in Young Women With Early Endometrial Carcinoma

Phase 2 Completed

Endometrial Neoplasms

NCT05316467 2025-08-11

Weight Management Plus Megestrol Acetate in Early-stage Endometrioid Carcinoma

Phase 2/3 Recruiting

GynecologicOther

Infertility, Obesity, Endometrial Neoplasms, Overweight

NCT05247268 2025-04-06

Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial Cancer

Phase 2 Recruiting

Endometrial Neoplasms

NCT05255653 2024-11-29

RAINBO

Phase 2/3 Recruiting

Endometrial Neoplasms

NCT06549855 2024-08-12

PD-1 Inhibitor Combined With Progesterone Treatment in FST for Patients With MMRd Endometrial Cancer

Phase NA Not yet recruiting

Turcot syndrome, Endometrial Neoplasms, Carcinoma, Endometrioid

NCT05913427 2024-08-01

PESETA

Phase 2 Recruiting

Adrenocortical Carcinoma

NCT06500234 2024-07-15

Nutrition Impact on Immunotherapy of Cancer

Phase 3 Recruiting

Neoplasms, Nutrition Disorders, Prosthesis Failure

NCT06417736 2024-05-16

Prospective Study for Endometrial Carcinoma and Hyperplasia in Childbearing-age Women

Phase NA Recruiting

Endometrial Hyperplasia, Endometrial Neoplasms

NCT03306472 2024-01-30

PIONEER

Phase 2 Completed

Breast Neoplasms

NCT05332483 2023-11-03

MA-EEC

Phase 1 Terminated

Endometrial Neoplasms

NCT03283488 2023-07-07

Comparison Between Mirtazapine and Megestrol for the Control of Anorexia-cachexia in Cancer Patients in Palliative Care.

Phase 2 Completed

Anorexia, Cachexia, Neoplasms

NCT03077698 2022-06-07

An Endometrial Cancer Study for Women With Recurrent or Persistent Endometrial Cancer

Phase 2 Terminated

25 enrolled 14 charts

Recurrence, Endometrial Neoplasms

NCT05380479 2022-05-18

Mirtazapine Versus Megestrol Acetate in Treatment of Anorexia-cachexia in Advanced Cancer Patients.

Phase 2 Unknown

Anorexia, Cachexia, Neoplasms

NCT02269670 2022-04-05

Phase II Study of Everolimus Beyond Progression

Phase 2 Terminated

3 enrolled 4 charts

Breast Neoplasms

NCT00006799 2021-09-09

Megestrol to Limit Weight Loss and Improve Quality of Life in Treating Patients With Head and Neck Cancer

Phase 3 Completed

Squamous Cell Carcinoma of Head and Neck, Anorexia, Cachexia, Head and Neck Neoplasms, Esthesioneuroblastoma, Olfactory

NCT00031785 2021-09-09

Megestrol in Treating Patients Who Are Undergoing Radiation Therapy for Lung Cancer

Phase 3 Completed

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00070148 2021-09-09

Oxandrolone Compared With Megestrol in Preventing Weight Loss in Patients Receiving Chemotherapy for Cancer

Phase 3 Completed

Body Weight Changes

NCT03241914 2020-11-20

Megestrol Acetate Plus LNG-IUS in Young Women With Early Endometrial Cancer

Phase 2/3 Completed

Endometrial Neoplasms

NCT00503581 2020-11-03

Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia

Phase 2 Terminated

9 enrolled 5 charts

Squamous Intraepithelial Lesions

NCT04430361 2020-06-12

the Efficacy and Safety of 5-HT3 Receptor Antagonist, Dexamethasone or Megestrol Acetate Dispersible Tablets in the Control of Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy

Phase 2 Unknown

Neoplasms, Vomiting

NCT03024580 2019-08-15

MEGA

Phase 2 Unknown

Breast Neoplasms

NCT00729586 2019-07-23

Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial Cancer

Phase 2 Completed

73 enrolled 13 charts

Endometrial Neoplasms

NCT00910091 2019-01-30

The Study of Oral Steroid Sulphatase Inhibitor BN83495 Versus Megestrol Acetate (MA) in Women With Advanced or Recurrent Endometrial Cancer

Phase 2 Completed

73 enrolled 19 charts

Endometrial Neoplasms

NCT03777930 2018-12-19

The Evaluation of Curative Effect on Treatment of Tumor Above Thalidomide Combined With Megestrol

Phase 4 Unknown

Neoplasms, Neoplasms, Second Primary

NCT00483327 2018-04-04

Management of Atypical Endometrial Hyperplasia and Endometrial Carcinoma Using Megestrol Acetate

Phase 2 Completed

31 enrolled 9 charts

Endometrial Hyperplasia, Endometrial Neoplasms

NCT02980653 2017-01-18

Megestrol Acetate Against Cancer-related Critical Body Weight Loss in Patients With H&N Cancer Who Receiving CCRT

Phase 2 Unknown

Head and Neck Neoplasms

NCT00031707 2016-07-14

Comparison of Megestrol and/or Omega-3 Fatty Acid-Enriched Nutritional Supplement in Treating Patients With Cancer-Related Weight Loss and Lack of Appetite

Phase 3 Completed

Anorexia, Cachexia

NCT00637728 2016-06-23

Treatment of Cancer-anorexia Using Megestrol Acetate Concentrated Suspension in Lung or Pancreatic Cancer Patients

Phase 3 Terminated

5 enrolled 8 charts

GastrointestinalThoracic

Anorexia, Body Weight, Cachexia, Lung Neoplasms, Pancreatic Neoplasms, Weight Loss

NCT00637806 2016-05-02

Treatment of Cancer-associated Anorexia Using Megestrol Acetate Concentrated Suspension

Phase 3 Terminated

4 enrolled 6 charts

Anorexia, Body Weight, Cachexia, Neoplasms, Weight Loss

NCT02619266 2015-12-04

The Safety and Effect Study of Acupuncture for Anorexia in Patients With Gastrointestinal Tract and Lung Cancers

Phase 2/3 Unknown

Anorexia

NCT01200602 2015-11-25

Megestrol Acetate in Treating Weight Loss or Anorexia in Young Patients With Malignancies Who Are Undergoing Radiation Therapy and/or Chemotherapy

Phase 2 Terminated

Anorexia, Body Weight Changes

NCT00005975 2015-11-18

S9626: Megestrol in Treating Hot Flashes Following Treatment for Breast Cancer

Phase 3 Completed

Breast Neoplasms, Hot Flashes

NCT00739830 2015-07-01

Clinical Trial of Ridaforolimus Compared to Progestin or Chemotherapy for Advanced Endometrial Carcinoma (MK-8669-007 AM6)

Phase 2 Completed

Endometrial Neoplasms

NCT01943058 2014-09-10

Megestrol Acetate or Levonorgestrel-Releasing Intrauterine System in Treating Patients With Atypical Endometrial Hyperplasia or Endometrial Cancer

Phase 2 Withdrawn

Endometrial Hyperplasia, Endometrial Neoplasms

NCT00066248 2014-02-03

Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment

Phase 2 Completed

CNSLymphoidMyeloidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Blast Crisis, Brain Neoplasms, Burkitt Lymphoma, Cachexia, Leukemia, Leukemia, Hairy Cell, Lymphoma, Medulloblastoma, Myelodysplastic Syndromes, Oligodendroglioma, Recurrence, Spinal Cord Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myelomonocytic, Chronic, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Dendritic Cell Sarcoma, Interdigitating

NCT01501396 2014-02-03

Megestrol Acetate With or Without Mirtazapine in Treating Cancer Patients With Weight Loss or Loss of Appetite

Phase 2 Withdrawn

Anorexia

NCT00002465 2013-11-06

High-Dose Megestrol in Treating Patients With Metastatic Breast Cancer, Endometrial Cancer, or Mesothelioma

Phase 1/2 Unknown

BreastGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant, Breast Neoplasms, Endometrial Neoplasms

NCT00041275 2013-09-20

Megestrol in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery

Phase 3 Completed

Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms

NCT00002680 2013-07-24

Sequential High-Dose Chemotherapy and Stem Cell Transplantation in Treating Patients With Chemotherapy-Sensitive Metastatic Breast Cancer

Phase 2 Completed

Breast Neoplasms