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Phase

Phase 2 2Phase 3 1Phase 1/2 1

Status

Completed 18Terminated 9Recruiting 9Unknown 7Not yet recruiting 5Active not recruiting 4Withdrawn 2

Sponsor Class

OTHER 3NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

Gynecologic 3Other hematologic neoplasm 1

Conditions

Endometrial Neoplasms 2Endometrial Hyperplasia 2Hematologic Neoplasms 1FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma 1Anorexia 1

Interventions

pembrolizumab 437Carboplatin 322Nivolumab 292Cyclophosphamide 281Specimen Handling 271Magnetic Resonance Spectroscopy 257Cisplatin 253Paclitaxel 248Radiotherapy 229Gemcitabine 183Biopsy 182Dexamethasone 181durvalumab 168atezolizumab 151Rituximab 138Doxorubicin 135Lenalidomide 134Bevacizumab 133Docetaxel 131Ipilimumab 129Capecitabine 120Radiation 118Oxaliplatin 114Radiosurgery 113Pemetrexed 112Etoposide 111Fluorouracil 110venetoclax 106fludarabine 106Prednisone 97

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Active not recruiting × Megestrol Acetate × Clear all
NCT03671811 2026-06-03

Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomy

City of Hope Medical Center

Phase 2 Active not recruiting
44 enrolled 12 charts
Gynecologic

Endometrial Hyperplasia, Endometrial Neoplasms

NCT05538897 2026-05-13

Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers

National Cancer Institute (NCI)

Phase 1/2 Active not recruiting
96 enrolled
Gynecologic

FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma

NCT04939090 2026-04-13

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

Alliance for Clinical Trials in Oncology

Phase 3 Active not recruiting
227 enrolled
Other hematologic neoplasm

Anorexia, Hematologic Neoplasms

NCT04576104 2026-01-21

Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

Northwestern University

Phase 2 Active not recruiting
51 enrolled
Gynecologic

Endometrial Hyperplasia, Endometrial Neoplasms

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