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Phase

Phase EARLY_PHASE1 1Phase 2 1Phase 1/2 1Phase 1 1

Status

Withdrawn 1Terminated 1Recruiting 1Completed 1

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

Other solid neoplasm 2Thoracic 1Other hematologic neoplasm 1

Conditions

Unspecified Adult Solid Tumor, Protocol Specific 1Pleural Effusion 1Lung Neoplasms 1Hematologic Neoplasms 1Adjuvant Chemotherapy 1

Interventions

Cisplatin 3193Cyclophosphamide 3187Carboplatin 2968Radiotherapy 2784Paclitaxel 2716Gemcitabine 2569pembrolizumab 2378Bevacizumab 2206Docetaxel 2196Fluorouracil 1848Capecitabine 1828Oxaliplatin 1738Dexamethasone 1604Nivolumab 1580Doxorubicin 1501Rituximab 1487Magnetic Resonance Spectroscopy 1382Etoposide 1345Irinotecan 1245Leucovorin 1222Drug Therapy 1202Cytarabine 1130Pemetrexed 1074fludarabine 1056Specimen Handling 1009Vincristine 964Cetuximab 943Prednisone 940Trastuzumab 940Lenalidomide 937

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Tissue Plasminogen Activator × Clear all
NCT06184321 2025-12-26

Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion

M.D. Anderson Cancer Center

Phase EARLY_PHASE1 Recruiting
30 enrolled
Other hematologic neoplasm

Hematologic Neoplasms

NCT03678090 2020-03-05

The Safety and Efficacy of Fibrinolysis in Patients With an Indwelling Pleural Catheter for Multi-loculated Malignant Pleural Effusion.

Yale University

Phase 2 Withdrawn
Thoracic

Lung Neoplasms, Pleural Effusion

NCT02492477 2018-08-21

TOP-TRIAL Safety of Not Flushing Non-used PORT-A-CATH® in Cancer Patients

Krankenhaus Barmherzige Schwestern Linz

Phase 1 Terminated
4 enrolled
Other solid neoplasm

Adjuvant Chemotherapy

NCT00086723 2012-06-11

In Vivo Angiostatin Generation Using Tissue Plasminogen Activator and Captopril in Treating Patients With Progressive Metastatic Cancer

Northwestern University

Phase 1/2 Completed
Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

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