Clinical Trials Browser

XL147 × Clear all

NCT01587040 2022-04-19

Open Label Treatment Extension Study With SAR245408 or SAR245409 as a Monotherapy or as a Combination Regimen

Phase 1/2 Completed

61 enrolled 13 charts

Neoplasms

NCT01013324 2016-06-03

Study of XL147 (SAR245408) in Advanced or Recurrent Endometrial Carcinoma

Phase 2 Completed

Endometrial Neoplasms

NCT01042925 2016-06-03

Study of XL147 (SAR245408) in Combination With Trastuzumab or Paclitaxel and Trastuzumab in Subjects With Metastatic Breast Cancer Who Have Progressed on a Previous Trastuzumab-based Regimen

Phase 1/2 Completed

Breast Neoplasms

NCT01082068 2016-06-03

Study of XL147 (SAR245408) or XL765 (SAR245409) in Combination With Letrozole in Subjects With Breast Cancer

Phase 1/2 Completed

Breast Neoplasms

NCT01943838 2016-04-22

A Study of the Safety and Pharmacokinetics of SAR245408 Tablets in Patients With Solid Tumors or Lymphoma

Phase 1 Completed

Neoplasms

NCT01357330 2016-04-01

Oral SAR245408 (XL147) and Oral MSC1936369B in Patients With Locally Advanced or Metastatic Solid Tumors

Phase 1 Completed

Neoplasm Metastasis

NCT00704392 2015-08-20

Safety Study of XL647 and XL147 Administered in Combination Daily in Adults With Solid Tumors

Phase 1 Withdrawn

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT01392924 2014-12-03

Safety and Pharmacokinetics of SAR245408 Daily Oral in Patients With Solid Tumors

Phase 1 Completed

Neoplasms

NCT01436565 2014-06-13

A Study of Investigational SAR256212 in Combination With SAR245408 in Patients With Solid Tumor Cancers

Phase 1 Completed

Other solid neoplasm

Solid Tumor Cancers

NCT00756847 2013-04-10

Safety Study of XL147 (SAR245408), in Combination With Paclitaxel and Carboplatin in Adults With Solid Tumors

Phase 1 Completed

GynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT00486135 2013-02-01

Study of the Safety and Pharmacokinetics of XL147 (SAR245408) in Adults With Solid Tumors or Lymphoma

Phase 1 Completed

Lymphoma, Neoplasms

NCT01240460 2012-07-27

Exploratory Study of XL765 (SAR245409) or XL147 (SAR245408) in Subjects With Recurrent Glioblastoma Who Are Candidates for Surgical Resection

Phase 1 Completed

Glioblastoma

NCT00692640 2012-03-23

Safety Study of XL147 (SAR245408) in Combination With Erlotinib in Adults With Solid Tumors

Phase 1 Completed

Carcinoma, Non-Small-Cell Lung, Neoplasms