Clinical Trials

211 enrolled

Breast Neoplasms

NCT05400603 2025-12-26

Aflac-NBL-2002

Phase 1 Recruiting

24 enrolled

CNSSarcoma

Neuroblastoma, Osteosarcoma

NCT06759064 2025-11-19

IPIZA

Phase 1/2 Recruiting

24 enrolled

Phase 1 Active not recruiting

Adenocarcinoma, Ascites, Stomach Neoplasms

NCT03173976 2025-11-06

Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial

17 enrolled

CNSLymphoidMyeloidOther hematologic neoplasmSarcoma

Chondrosarcoma

NCT02508038 2025-10-16

Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

Phase 1 Recruiting

22 enrolled

Hodgkin Disease, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Leukemia, Myeloid, Acute, Neuroectodermal Tumors, Primitive, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05080790 2025-08-17

DiTuSarc

7 enrolled

Phase NA Active not recruiting

Leiomyosarcoma

NCT06876636 2025-07-29

Zoledronic Acid Combined With EC-T for Triple-Negative Breast Cancer

99 enrolled

Phase 3 Active not recruiting

Breast Cancer Metastatic

NCT06513624 2025-07-25

ETC-159-02

Phase 1 Recruiting

16 enrolled

Gynecologic

With MSS/pMMR Advanced, Platinum-resistant Ovarian Cancer

NCT00470223 2025-06-08

OS2006

318 enrolled

Sarcoma, Osteosarcoma

NCT02517918 2025-06-08

METZOLIMOS

23 enrolled 15 charts

Phase 2 Active not recruiting

Osteosarcoma

NCT03073785 2025-05-25

Hypofractionated Stereotactic Body Radiation & Fluorouracil or Capecitabine for Locally Advanced Pancreatic Cancer

46 enrolled

Pancreatic Neoplasms

NCT03958565 2025-05-21

Response of Bony Metastasis to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancers With Actionable Driver Mutations.

Recruiting

100 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01671774 2024-11-14

PILOT

29 enrolled

CLDN18.2-positive Gastric Adenocarcinoma

NCT00365105 2024-09-20

Zoledronate, Vitamin D, and Calcium With or Without Strontium 89 or Samarium 153 in Preventing or Delaying Bone Problems in Patients With Bone Metastases From Prostate Cancer, Lung Cancer, or Breast Cancer

BreastGenitourinaryThoracic

261 enrolled 12 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Pain, Prostatic Neoplasms

NCT03336983 2024-08-01

BonEnza

126 enrolled

Prostatic Neoplasms

NCT00733538 2024-04-12

IFM-01-04

89 enrolled

Plasma cell

Multiple Myeloma

NCT00295646 2024-03-15

Tamoxifen Versus Anastrozole, Alone or in Combination With Zoledronic Acid

1,803 enrolled 20 charts

Phase 3 Not yet recruiting

Breast Neoplasms

NCT06221072 2024-01-24

A Study to Assess the Prevention of Bone-related Events in Patients With Bone Metastases From Malignant Solid Tumors Treated With JMT103 Compared to Zoledronic Acid

1,360 enrolled

Imaging Examination Shows at Least One Site With Bone Metastases From Soild Tumors

NCT00525759 2023-11-24

ANZAC

40 enrolled

Breast Neoplasms

NCT03358017 2023-10-19

YAPPETIZER

54 enrolled

Triple Negative Breast Neoplasms

NCT00172029 2023-08-18

Study Comparing Full-dose Radiotherapy Versus Reduced Dose in the Management of Bone Metastasis in Patients With Breast Cancer Receiving Zoledronic Acid

116 enrolled

Breast Neoplasms

NCT00556374 2023-07-27

Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy

3,420 enrolled 19 charts

Breast Neoplasms

NCT05866172 2023-05-19

HAIC Combined Withzoledronic Acid for the Prevention of Bone Metastases in Advanced HCC

Phase 3 Unknown

264 enrolled

Phase 2/3 Active not recruiting

Carcinoma, Hepatocellular

NCT00268476 2023-04-18

STAMPEDE

11,992 enrolled

Prostatic Neoplasms

NCT00885326 2023-04-10

N2007-02:Bevacizumab,Cyclophosphamide,& Zoledronic Acid in Patients W/ Recurrent or Refractory High-Risk Neuroblastoma

29 enrolled

CNS

Neuroblastoma

NCT00412022 2023-03-24

HOBOE

Phase 3 Unknown

1,294 enrolled

Breast Neoplasms

NCT02286830 2023-02-17

Magnolia

158 enrolled

Plasma cell

Multiple Myeloma, Osteolysis, Osteonecrosis

NCT00321464 2022-11-08

A Study Comparing Denosumab vs. Zoledronic Acid for the Treatment of Bone Metastases in Breast Cancer Subjects.

2,049 enrolled 16 charts

Breast Neoplasms, Fractures, Bone

NCT01345019 2022-11-08

Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma

Other hematologic neoplasmPlasma cellSarcoma

1,718 enrolled 22 charts

Blood Protein Disorders, Bone Diseases, Bone Marrow Diseases, Bone Neoplasms, Hematologic Diseases, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Neoplastic Processes, Paraproteinemias, Spinal Cord Compression, Hematologic Neoplasms, Fractures, Bone, Neoplasms, Plasma Cell

NCT00330759 2022-11-07

Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma.

1,779 enrolled 14 charts

LymphoidPlasma cell

Lymphoma, Multiple Myeloma, Spinal Cord Compression

NCT00458796 2022-05-27

Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone

Phase NA Terminated

1,500 enrolled

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Neoplasm Metastasis, Pain, Breast Neoplasms, Male

NCT00566618 2022-02-25

Dasatinib in Combination With Zoledronic Acid for the Treatment of Breast Cancer With Bone Metastasis

Phase 1/2 Completed

31 enrolled 8 charts

Breast Neoplasms

NCT05164952 2021-12-21

Delayed Versus Immediate Use Of Zoledronic Acid For Postmenopausal Patients With Early Breast Cancer Who Are Using Adjuvant Letrozole

Phase 3 Unknown

50 enrolled

Breast Neoplasms

NCT01951586 2021-10-25

Denosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer

226 enrolled 24 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT03408652 2021-10-22

MOSCAR

Phase 3 Terminated

1 enrolled

Carcinoma, Renal Cell

NCT04045522 2021-07-20

Study on Bisphosphonates Targeting Triple-negative Breast Cancer

Unknown

120 enrolled

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT00127205 2021-07-02

S0307 Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer.

6,097 enrolled 20 charts

Breast Neoplasms

NCT01623908 2021-06-22

BLAZE

Phase NA Terminated

200 enrolled

Bone Diseases, Metabolic, Breast Neoplasms

NCT00622505 2021-05-26

Z-MARK

121 enrolled 15 charts

Plasma cell

Multiple Myeloma

NCT00424983 2020-12-21

Study of Zoledronic Acid Administered Monthly Versus Every 3 Months in Multiple Myeloma and Breast Cancer Patients Who Were Treated With Zoledronic Acid the Prior Year

18 enrolled

BreastPlasma cell

Breast Neoplasms, Multiple Myeloma

NCT00058188 2020-12-08

Zolendronate for the Prevention of Bone Loss in Men w/ Prostate CA on Long-Term Androgen Deprivation

Phase 3 Terminated

53 enrolled

Osteoporosis, Prostatic Neoplasms

NCT02721433 2020-12-02

REaCT-BTA

263 enrolled

BreastGenitourinary

Breast Neoplasms, Neoplasm Metastasis, Prostatic Neoplasms

NCT04325776 2020-10-12

A Study of AL2846 Versus Zoledronic Acid in Subjects With Advanced Non-Small Cell Lung Cancer With Bone Metastasis

Phase 2 Unknown

60 enrolled

Thoracic

Bone Metastatic Non-small Cell Lung Cancer

NCT04488614 2020-07-30

PBCB

Enrolling by invitation

1,200 enrolled

Breast Neoplasms, Fatigue

NCT00079001 2020-05-12

Zoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone Metastases

645 enrolled 13 charts