Clinical Trials

Breast Neoplasms

NCT06625190 2026-03-11

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

Phase 1/2 Recruiting

27 enrolled

CNSSarcoma

Chordoma, Myoepithelioma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Sarcoma, Clear Cell, Sarcoma, Alveolar Soft Part, Nerve Sheath Neoplasms, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT03664687 2026-02-09

REaCT-ZOL

211 enrolled

Breast Neoplasms

NCT06374459 2026-02-09

Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis

Phase 1/2 Recruiting

152 enrolled

Breast Neoplasms

NCT05400603 2025-12-26

Aflac-NBL-2002

Phase 1 Recruiting

24 enrolled

CNSSarcoma

Neuroblastoma, Osteosarcoma

NCT06759064 2025-11-19

IPIZA

Phase 1/2 Recruiting

24 enrolled

Phase 1 Active not recruiting

Adenocarcinoma, Ascites, Stomach Neoplasms

NCT03173976 2025-11-06

Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial

17 enrolled

CNSLymphoidMyeloidOther hematologic neoplasmSarcoma

Chondrosarcoma

NCT02508038 2025-10-16

Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

Phase 1 Recruiting

22 enrolled

Hodgkin Disease, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Leukemia, Myeloid, Acute, Neuroectodermal Tumors, Primitive, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03295981 2025-10-15

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

Phase 3 Recruiting

120 enrolled

Giant Cell Tumor of Bone

NCT05080790 2025-08-17

DiTuSarc

7 enrolled

Phase NA Active not recruiting

Leiomyosarcoma

NCT06876636 2025-07-29

Zoledronic Acid Combined With EC-T for Triple-Negative Breast Cancer

99 enrolled

Phase 2 Not yet recruiting

Breast Cancer Metastatic

NCT06513624 2025-07-25

ETC-159-02

Phase 1 Recruiting

16 enrolled

Gynecologic

With MSS/pMMR Advanced, Platinum-resistant Ovarian Cancer

NCT07043608 2025-07-02

ZAMBONI

20 enrolled

Genitourinary

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Neoplasm Metastasis

NCT00470223 2025-06-08

OS2006

Phase 3 Active not recruiting

318 enrolled

Sarcoma, Osteosarcoma

NCT02517918 2025-06-08

METZOLIMOS

Phase 1 Completed

23 enrolled 15 charts

Phase 2 Active not recruiting

Osteosarcoma

NCT03073785 2025-05-25

Hypofractionated Stereotactic Body Radiation & Fluorouracil or Capecitabine for Locally Advanced Pancreatic Cancer

46 enrolled

Pancreatic Neoplasms

NCT01671774 2024-11-14

PILOT

Phase 1 Completed

29 enrolled

CLDN18.2-positive Gastric Adenocarcinoma

NCT00365105 2024-09-20

Zoledronate, Vitamin D, and Calcium With or Without Strontium 89 or Samarium 153 in Preventing or Delaying Bone Problems in Patients With Bone Metastases From Prostate Cancer, Lung Cancer, or Breast Cancer

BreastGenitourinaryThoracic

261 enrolled 12 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Pain, Prostatic Neoplasms

NCT03336983 2024-08-01

BonEnza

126 enrolled

Genitourinary

Prostatic Neoplasms

NCT00733538 2024-04-12

IFM-01-04

89 enrolled

Plasma cell

Multiple Myeloma

NCT00295646 2024-03-15

Tamoxifen Versus Anastrozole, Alone or in Combination With Zoledronic Acid

1,803 enrolled 20 charts

Phase 3 Not yet recruiting

Breast Neoplasms

NCT06221072 2024-01-24

A Study to Assess the Prevention of Bone-related Events in Patients With Bone Metastases From Malignant Solid Tumors Treated With JMT103 Compared to Zoledronic Acid

1,360 enrolled

Imaging Examination Shows at Least One Site With Bone Metastases From Soild Tumors

NCT00525759 2023-11-24

ANZAC

40 enrolled

Breast Neoplasms

NCT03358017 2023-10-19

YAPPETIZER

54 enrolled

Triple Negative Breast Neoplasms

NCT00172029 2023-08-18

Study Comparing Full-dose Radiotherapy Versus Reduced Dose in the Management of Bone Metastasis in Patients With Breast Cancer Receiving Zoledronic Acid

116 enrolled

Breast Neoplasms

NCT00556374 2023-07-27

Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy

3,420 enrolled 19 charts

Breast Neoplasms

NCT05866172 2023-05-19

HAIC Combined Withzoledronic Acid for the Prevention of Bone Metastases in Advanced HCC

Phase 3 Unknown

264 enrolled

Phase 2/3 Active not recruiting

Carcinoma, Hepatocellular

NCT00268476 2023-04-18

STAMPEDE

11,992 enrolled

Genitourinary

Prostatic Neoplasms

NCT00885326 2023-04-10

N2007-02:Bevacizumab,Cyclophosphamide,& Zoledronic Acid in Patients W/ Recurrent or Refractory High-Risk Neuroblastoma

Phase 1 Completed

29 enrolled

CNS

Neuroblastoma

NCT00412022 2023-03-24

HOBOE

Phase 3 Unknown

1,294 enrolled

Breast Neoplasms

NCT02286830 2023-02-17

Magnolia

158 enrolled

Plasma cell

Multiple Myeloma, Osteolysis, Osteonecrosis

NCT00321464 2022-11-08

A Study Comparing Denosumab vs. Zoledronic Acid for the Treatment of Bone Metastases in Breast Cancer Subjects.

2,049 enrolled 16 charts

Breast Neoplasms, Fractures, Bone

NCT01345019 2022-11-08

Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma