Clinical Trials
21 trialsNCT05583552 2026-05-12
IMpress
GCP-Service International West GmbH
Phase 2 Active not recruiting
NCT07549451 2026-04-24
Phase 2 Study Of Imetelstat for Patient With Myelodysplastic/Myeloproliferative Neoplasms
M.D. Anderson Cancer Center
Phase 2 Not yet recruiting
NCT07320235 2026-04-22
IMAGINE
Icahn School of Medicine at Mount Sinai
Phase 1 Recruiting
NCT06247787 2026-04-20
A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy
Children's Oncology Group
Phase 1 Recruiting
NCT02598661 2026-01-05
Study to Evaluate Imetelstat (GRN163L) in Participants With International Prognostic Scoring System (IPSS) Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)
Geron Corporation
Phase 2/3 Active not recruiting
NCT04576156 2025-12-04
A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment
Geron Corporation
Phase 3 Active not recruiting
NCT01731951 2021-09-21
Imetelstat Sodium in Treating Participants With Primary or Secondary Myelofibrosis
Geron Corporation
Phase 2 Completed
NCT01916187 2020-09-21
Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma
Canadian Cancer Trials Group
Phase 1 Withdrawn
NCT02011126 2018-08-07
Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors
Children's Oncology Group
Phase 2 Withdrawn
NCT01836549 2018-07-20
Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors
Pediatric Brain Tumor Consortium
Phase 2 Terminated
NCT01242930 2016-05-12
Open Label Study With Imetelstat to Determine Effect of Imetelstat in Patients w/ Previously Treated Multiple Myeloma
Geron Corporation
Phase 2 Completed
NCT01137968 2016-01-26
Imetelstat as Maintenance Therapy After Initial Induction Chemotherapy in Non-small Cell Lung Cancer (NSCLC)
Geron Corporation
Phase 2 Completed
NCT01243073 2016-01-26
ET/PV
Geron Corporation
Phase 2 Completed
NCT01256762 2016-01-26
Imetelstat in Combination With Paclitaxel (With or Without Bevacizumab) in Patients With Locally Recurrent or Metastatic Breast Cancer
Geron Corporation
Phase 2 Completed
NCT00310895 2015-12-24
Safety and Dose Study of GRN163L Administered to Patients With Refractory or Relapsed Solid Tumor Malignancies
Geron Corporation
Phase 1 Completed
NCT00510445 2015-12-24
Study of GRN163L With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Non Small Cell Lung Cancer
Geron Corporation
Phase 1 Completed
NCT00594126 2015-12-24
Safety and Dose Study of GRN163L Administered to Treat Patients With Refractory or Relapsed Multiple Myeloma
Geron Corporation
Phase 1 Completed
NCT00718601 2015-12-24
Safety and Dose Study of GRN163L and Velcade to Treat Patients With Refractory or Relapsed Myeloma
Geron Corporation
Phase 1 Completed
NCT01265927 2015-10-27
A Study Inhibiting Telomerase to Reverse Trastuzumab Resistance in HER2+ Breast Cancer
Indiana University
Phase 1 Completed
NCT01273090 2014-01-30
Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma
Children's Oncology Group
Phase 1 Completed
NCT01568632 2012-11-21
Imetelstat for Children With Refractory or Recurrent Solid Tumors and Lymphoma
National Institutes of Health Clinical Center (CC)
Phase 1 Withdrawn