Announcements Trials
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Phase

Phase 4 2Phase 3 1Phase 2/3 1Phase 2 1

Status

Withdrawn 3Recruiting 1Completed 1

Sponsor Class

INDUSTRY 3OTHER 2

Study Type

Interventional 5

Sponsor

Cancer Type

Other 2Gastrointestinal 2Head & Neck 1

Conditions

Pancreatic Neoplasms 2Squamous Cell Carcinoma of Head and Neck 1Opioid-Related Disorders 1Opioid-Induced Constipation 1Neoplasms 1Constipation 1

Interventions

Cisplatin 3193Cyclophosphamide 3187Carboplatin 2968Radiotherapy 2784Paclitaxel 2716Gemcitabine 2569pembrolizumab 2378Bevacizumab 2206Docetaxel 2196Fluorouracil 1848Capecitabine 1828Oxaliplatin 1738Dexamethasone 1604Nivolumab 1580Doxorubicin 1501Rituximab 1487Magnetic Resonance Spectroscopy 1382Etoposide 1345Irinotecan 1245Leucovorin 1222Drug Therapy 1202Cytarabine 1130Pemetrexed 1074fludarabine 1056Specimen Handling 1009Vincristine 964Cetuximab 943Prednisone 940Trastuzumab 940Lenalidomide 937

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
methylnaltrexone × Clear all
NCT06162377 2025-12-17

Methylnatrexone In Resectable Head and Neck Squamous Cell Carcinoma (MINK). A "Window of Opportunity" Pilot Study.

M.D. Anderson Cancer Center

Phase 4 Recruiting
25 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT04083651 2021-05-07

A Study of Methylnaltrexone Bromide (MNTX) in Participants With Advanced Pancreatic Cancer

Bausch Health Americas, Inc.

Phase 2/3 Withdrawn
Gastrointestinal

Pancreatic Neoplasms

NCT04151719 2021-05-07

An Extension Study of Methylnaltrexone Bromide (MNTX) in Participants With Advanced Pancreatic Cancer

Bausch Health Americas, Inc.

Phase 3 Withdrawn
Gastrointestinal

Pancreatic Neoplasms

NCT00858754 2019-11-29

Study Evaluating Safety & Efficacy of Subcutaneous Methylnaltrexone on Opioid-Induced Constipation in Cancer Subjects

Bausch Health Americas, Inc.

Phase 4 Withdrawn
Other

Opioid-Induced Constipation

NCT01004393 2016-02-02

Methylnaltrexone for Opioid-induced Constipation in Cancer Patients

University of Vermont

Phase 2 Completed
12 enrolled 10 charts
Other

Constipation, Opioid-Related Disorders, Neoplasms

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