Clinical Trials Browser

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT07268677 2025-12-08

A Single-arm Clinical Study Evaluating Pirfenidone and Sintilimab in Combination With Standard Neoadjuvant Chemotherapy for Colorectal Cancer Patients With Peritoneal Metastasis.

Phase 2 Not yet recruiting

30 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT03177291 2025-12-05

Pirfenidone Combined With Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC

Phase 1 Completed

48 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT07161791 2025-09-09

Camrelizumab, Pirfenidone, and Chemotherapy in the Treatment of Advanced Triple-Negative Breast Cancer

Phase 1/2 Not yet recruiting

12 enrolled

Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT05704166 2025-08-08

PirfenidoneVsPlacebo as Prophylaxis Against Acute Radiation-induced Lung Injury Following HFRT in Breast Cancer Patients

Phase 2 Recruiting

214 enrolled

Breast

Breast Neoplasms, Acute Lung Injury

NCT06484153 2024-07-03

Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma

Phase 1/2 Not yet recruiting

25 enrolled

Gastrointestinal

To Evaluate the Efficacy of Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Colorectal Carcinoma

NCT04243837 2024-04-23

LYT-100 in Patients With BCRL

Phase 2 Terminated

50 enrolled 9 charts

Lymphedema

NCT05801133 2024-03-15

Pifenidone Prophylactic Therapy for Radiation Lung Injury in Patients Who Have Previously Received Immune Checkpoint Inhibitors

Phase 2 Unknown

41 enrolled

Thoracic

Lung Neoplasms

NCT06142318 2023-11-21

Pirfenidone as a Radiosensitizer in the Treatment of Head and Neck Squamous Cell Carcinoma

Phase 2 Unknown

66 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT05280873 2022-03-15

Pirfenidone Combined With Methylprednisolone Versus Methylprednisolone in the Treatment of CIP

Phase 1 Unknown

48 enrolled

Neoplasms, Pneumonia

NCT00076102 2018-04-23

Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas

Phase 2 Completed

36 enrolled 13 charts

CNS

Neurofibromatosis 1, Nerve Sheath Neoplasms, Neurofibroma, Plexiform

NCT00332033 2017-07-02

Development of a Non-Invasive Treatment for Uterine Leiomyoma (Fibroids)

Phase 2 Completed

32 enrolled

Leiomyoma, Myofibroma

NCT00053937 2015-04-30

Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas

Phase 1 Completed

CNSOther neoplasm

Neurofibromatosis 1, Precancerous Conditions, Neurofibroma, Plexiform

NCT00020631 2013-06-19

Pirfenidone in Treating Patients With Fibrosis Caused by Radiation Therapy for Cancer

Phase NA Completed

Radiation Fibrosis Syndrome

NCT00754780 2012-03-19

Clinical Trial of Pirfenidone in Adult Patients With Neurofibromatosis 1

Phase 2 Completed

24 enrolled

CNS

Neurofibromatoses, Neurofibroma, Plexiform

Clinical Trials

Combination of Atezolizumab and Pirfenidone in Second-line and Beyond NSCLC

A Single-arm Clinical Study Evaluating Pirfenidone and Sintilimab in Combination With Standard Neoadjuvant Chemotherapy for Colorectal Cancer Patients With Peritoneal Metastasis.

Pirfenidone Combined With Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC

Camrelizumab, Pirfenidone, and Chemotherapy in the Treatment of Advanced Triple-Negative Breast Cancer

PirfenidoneVsPlacebo as Prophylaxis Against Acute Radiation-induced Lung Injury Following HFRT in Breast Cancer Patients

Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma

LYT-100 in Patients With BCRL

Pifenidone Prophylactic Therapy for Radiation Lung Injury in Patients Who Have Previously Received Immune Checkpoint Inhibitors

Pirfenidone as a Radiosensitizer in the Treatment of Head and Neck Squamous Cell Carcinoma

Pirfenidone Combined With Methylprednisolone Versus Methylprednisolone in the Treatment of CIP

Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas

Development of a Non-Invasive Treatment for Uterine Leiomyoma (Fibroids)

Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas

Pirfenidone in Treating Patients With Fibrosis Caused by Radiation Therapy for Cancer

Clinical Trial of Pirfenidone in Adult Patients With Neurofibromatosis 1