Announcements Trials
Browse Landscape

Phase

Phase 2 3Phase 1 2Phase NA 1

Status

Completed 6Unknown 3Not yet recruiting 3Recruiting 2Terminated 1

Sponsor Class

NIH 4OTHER 2

Study Type

Interventional 6

Sponsor

Cancer Type

CNS 3Thoracic 1Other neoplasm 1

Conditions

Neurofibroma, Plexiform 3Neurofibromatosis 1 2Radiation Fibrosis Syndrome 1Precancerous Conditions 1Neurofibromatoses 1Nerve Sheath Neoplasms 1Myofibroma 1Lung Neoplasms 1Leiomyoma 1Carcinoma, Non-Small-Cell Lung 1

Interventions

Cyclophosphamide 1499Cisplatin 1435Paclitaxel 1340Radiotherapy 1310Carboplatin 1267Gemcitabine 1226Docetaxel 1133Bevacizumab 1070Fluorouracil 906Doxorubicin 805Dexamethasone 755Rituximab 744Capecitabine 735Oxaliplatin 709pembrolizumab 700Etoposide 679Irinotecan 639Filgrastim 624Cytarabine 587Nivolumab 586Leucovorin 583Vincristine 517Cetuximab 479Prednisone 478Bortezomib 474Trastuzumab 468Erlotinib Hydrochloride 467Surveys and Questionnaires 460Methotrexate 444Lenalidomide 436

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Completed × pirfenidone × Clear all
NCT03177291 2025-12-05

Pirfenidone Combined With Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC

H. Lee Moffitt Cancer Center and Research Institute

Phase 1 Completed
48 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00076102 2018-04-23

Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
36 enrolled 13 charts
CNS

Neurofibromatosis 1, Nerve Sheath Neoplasms, Neurofibroma, Plexiform

NCT00332033 2017-07-02

Development of a Non-Invasive Treatment for Uterine Leiomyoma (Fibroids)

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
32 enrolled

Leiomyoma, Myofibroma

NCT00053937 2015-04-30

Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas

National Cancer Institute (NCI)

Phase 1 Completed
CNSOther neoplasm

Neurofibromatosis 1, Precancerous Conditions, Neurofibroma, Plexiform

NCT00020631 2013-06-19

Pirfenidone in Treating Patients With Fibrosis Caused by Radiation Therapy for Cancer

National Cancer Institute (NCI)

Phase NA Completed

Radiation Fibrosis Syndrome

NCT00754780 2012-03-19

Clinical Trial of Pirfenidone in Adult Patients With Neurofibromatosis 1

Mayo Clinic

Phase 2 Completed
24 enrolled
CNS

Neurofibromatoses, Neurofibroma, Plexiform

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