Announcements Trials
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Phase

Phase 1 4Phase 2 1

Status

Terminated 2Active not recruiting 2Completed 1

Sponsor Class

NIH 4INDUSTRY 1

Study Type

Interventional 5

Sponsor

Cancer Type

Gastrointestinal 2CNS 2Other hematologic neoplasm 1Lymphoid 1

Conditions

Rectal Neoplasms 2Stomach Neoplasms 1Neoplasms 1Lymphoma 1Liver Neoplasms 1Hematologic Neoplasms 1Glioblastoma 1Esophageal Neoplasms 1Colonic Neoplasms 1Brain Neoplasms 1

Interventions

Cisplatin 3202Cyclophosphamide 3195Carboplatin 2977Radiotherapy 2790Paclitaxel 2718Gemcitabine 2572pembrolizumab 2385Bevacizumab 2209Docetaxel 2199Fluorouracil 1851Capecitabine 1833Oxaliplatin 1742Dexamethasone 1605Nivolumab 1581Doxorubicin 1501Rituximab 1488Magnetic Resonance Spectroscopy 1387Etoposide 1346Irinotecan 1248Leucovorin 1226Drug Therapy 1205Cytarabine 1130Pemetrexed 1076fludarabine 1063Specimen Handling 1017Vincristine 964Cetuximab 945Trastuzumab 945Prednisone 942Lenalidomide 937

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
ropidoxuridine × Clear all
NCT02993146 2026-04-30

Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases

National Cancer Institute (NCI)

Phase 1 Active not recruiting
11 enrolled 12 charts
CNSOther hematologic neoplasm

Brain Neoplasms, Hematologic Neoplasms

NCT02381561 2026-04-13

Ropidoxuridine in Treating Patients With Advanced Gastrointestinal Cancer Undergoing Radiation Therapy

National Cancer Institute (NCI)

Phase 1 Active not recruiting
19 enrolled
Gastrointestinal

Colonic Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT06359379 2025-12-18

Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter

Shuttle Pharmaceuticals, Inc.

Phase 2 Terminated
30 enrolled
CNS

Glioblastoma

NCT04406857 2025-02-26

Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer

National Cancer Institute (NCI)

Phase 1 Terminated
1 enrolled 7 charts
Gastrointestinal

Rectal Neoplasms

NCT01240577 2018-10-18

An Early Phase I Study of IPdR Absorption, Metabolism, and Safety in Patients With Advanced Solid Tumors and Lymphomas

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
10 enrolled
Lymphoid

Lymphoma, Neoplasms

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