Clinical Trials Browser

trastuzumab duocarmazine × Clear all

NCT01042379 2026-05-06

I-SPY

Phase 2 Recruiting

Pathologic Complete Response, Breast Neoplasms, Hemangiosarcoma, Neoplasms, Triple Negative Breast Neoplasms

NCT04205630 2024-05-30

SYD985 in Patients With HER2-expressing Recurrent, Advanced or Metastatic Endometrial Carcinoma

Phase 2 Completed

64 enrolled 13 charts

Endometrial Neoplasms

NCT04235101 2024-01-05

Phase I Study of SYD985 With Niraparib in Patients With Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumor

NCT04983238 2024-01-05

Evaluation of Safety and Efficacy of Sodium Thiosulfate (BYON5667) Eye Drops to Reduce Ocular Toxicity in Cancer Patients Treated With SYD985

Phase 1/2 Completed

Breast Neoplasms

NCT04602117 2023-11-18

ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer

Phase 1 Withdrawn

BreastGenitourinaryGynecologic

Urinary Bladder Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT03262935 2023-10-19

TULIP

Phase 3 Completed

437 enrolled 17 charts

Breast Neoplasms

NCT02277717 2023-08-14

First-in-human Study With the Antibody-drug Conjugate SYD985 to Evaluate Safety and Efficacy in Cancer Patients

Phase 1 Completed

Neoplasm Metastasis, Neoplasms